JCM, Free Full-Text
By A Mystery Man Writer
Last updated 21 Sept 2024
Down syndrome (DS) is a form of accelerated aging, and people with DS are highly prone to aging-related conditions that include vascular and neurological disorders. Due to the overexpression of several genes on Chromosome 21, for example genes encoding amyloid precursor protein (APP), superoxide dismutase (SOD), and some of the interferon receptors, those with DS exhibit significant accumulation of amyloid, phospho-tau, oxidative stress, neuronal loss, and neuroinflammation in the brain as they age. In this review, we will summarize the major strides in this research field that have been made in the last few decades, as well as discuss where we are now, and which research areas are considered essential for the field in the future. We examine the scientific history of DS bridging these milestones in research to current efforts in the field. We extrapolate on comorbidities associated with this phenotype and highlight clinical networks in the USA and Europe pursuing clinical research, concluding with funding efforts and recent recommendations to the NIH regarding DS research.
Jcm Font: Download for Free, Online
JCM, Free Full-Text
JCM, Free Full-Text, nelson games sbo
Jcm Free Full Text Sex Differences Are Here To Stay Relevance To 44672
JCM, Free Full-Text, halimeter
Journal of Clinical Medicine An Open Access Journal from MDPI
Jcm Multiplex
Images
JCM Free Full-Text Pathophysiology And Clinical Management, 56% OFF
Recommended for you
- Anger Management Gridley, CA: Counseling, Therapy and Treatment.14 Jul 2023
- Nini Gridley — Yoga Mandali14 Jul 2023
- Gridley Invitational: 2024 and 2025 - Prep Hoops14 Jul 2023
- Two-car accident on Gridley and Alondra14 Jul 2023
- Driver dies after collision on Highway 99 in Gridley Wednesday14 Jul 2023
- Nini Gridley - Bach Foundation Registered Practitioner - Full14 Jul 2023
- Flight: Two, an art print by Liz Gridley - INPRNT14 Jul 2023
- 2021 Official Vero Beach Handbook by Palm Beach Media Group - Issuu14 Jul 2023
- Pregnancy Planner14 Jul 2023
- Carole Gridley - Self-employed14 Jul 2023
You may also like
- Fantasie Aubree Side Support Bra14 Jul 2023
- Fiery Force, Red high waisted gym leggings14 Jul 2023
- Football - Southeastern University Athletics14 Jul 2023
- Mermaid and Retro Vibes: Spring Swim with Lane Bryant — Sarah Sapora14 Jul 2023
- Total Lunar Eclipse in store for next Tuesday14 Jul 2023
- Women's Cotton / Spandex Super Soft Tank - Samoan Tattoo Kuahiwi Design14 Jul 2023
- LESSO 4 In. ABS Cap Hub14 Jul 2023
- Dick's Sporting Goods Jamie Sadock Women's Skinnylicious Knee Golf Capri Shorts14 Jul 2023
- Men's Track & Field - Flagler College Athletics14 Jul 2023
- Multi Exercises Home Gym with Back Cover (150 lbs)14 Jul 2023